This depends on which formula you’re taking. If you are enjoying Do Not Disturb™, for example, this formula is best taken in the evening when you’re looking to wind down and have restful sleep. While Slay All Day™ is a caffeinated formula and is best taken before 3pm. Refer to your formula’s specific instructions for the best time of day to use. Or visit our Shop and view the product detail page of the formula you want to take.